| Rank | Entry Num | Name | School | Region | Efficiency |
| 1 | 38 | Hussain, Abrar | Grover Cleveland High School | Brooklyn-Queens-Staten Island | 3190 |
| 2 | 4 | Jansma, Quinn | Squalicum High School | Western Washington | 2625 |
| 3 | 27 | Yang, David | Troy High School | Orange County California | 2532 |
| 4 | 55 | Munroe, Tannor | Squalicum High School | Western Washington | 2416 |
| 5 | 18 | Zheng, David | San Marino High School | Orange County California | 2263 |
| 6 | 46 | Grah, Nathan | Lincoln Way North High School | Chicago South Suburban | 2098 |
| 7 | 21 | Acob, VaRey | Cowan-Sunset High School | Southern Nevada | 2000 |
| 8 | 3 | Hoover, Amy | Loyola Academy | Chicago North Suburban | 1989 |
| 9 | 35 | Chung, LeAnn | Clark High School | Southern Nevada | 1984 |
| 10 | 28 | Biere, Ferdinand | Ozark High School | Ozark Missouri | 1951 |
| 11 | 26 | Samek, Oli | Nestucca High School | Oregon | 1690 |
| 12 | 54 | Hoffmann, Billy | Loyola Academy | Chicago North Suburban | 1559 |
| 13 | 29 | Xia, Andy | Westlake High School | Los Angeles-Ventura County | 1524 |
| 14 | 52 | Chen, Wun-Min | McKinley High School | Hawaii | 1469 |
| 15 | 12 | Walters, Tommy | Wenatchee High School | Central Washington | 1332 |
| 16 | 37 | Moreno, Steven | Robert H. Lewis High School | Los Angeles City | 1329 |
| 17 | 17 | Grayson, Nicholas | Riverdale High School | Conde McCullough Oregon | 1307 |
| 18 | 25 | Geronimo, Neil | Amundsen High School | Chicago City | 1292 |
| 19 | 20 | Min, Si Thu | Glencliff High School | Nashville | 1212 |
| 20 | 49 | Conrad, Alyssa | Dover High School | Tuscawaras Valley Ohio | 1154 |
| Rank | Entry Num | Name | School | Region | Efficiency |
| 21 | 7 | Kolcharno, Kyle | Valley View High School | Northeast Pennsylvania | 1146 |
| 22 | 32 | Martinez, Brian | G. Holmes Braddock High School | Miami-Dade SECME | 1125 |
| 23 | 31 | Maack, Gina | Nestucca High School | Conde McCullough Oregon | 1097 |
| 24 | 48 | Sy, Christian | Los Angeles Senior High School | Los Angeles City | 1092 |
| 25 | 14 | Blackburn, Jonathan | Rockwall Heath High School | North Texas | 1087 |
| 26 | 13 | Sotolonga, Maria Karla | Pinecrest Prep High School | Miami-Dade Science Fair | 1049 |
| 27 | 19 | Wheat, Andrew | Ozark High School | Ozark Missouri | 1037 |
| 28 | 47 | Bass, Ryan | Rockwall Heath High School | North Texas | 919 |
| 29 | 11 | Nakagawa, Shiori | McKinley High School | Hawaii | 871 |
| 30 | 23 | Alam, Mohammad | Simi Valley High School | Los Angeles-Ventura County | 842 |
| 31 | 53 | Benedict, Benjamin | Whitney Young High School | Chicago City | 821 |
| 32 | 41 | Mejia, Evelyn | Cashmere High School | Central Washington | 802 |
| 33 | 2 | Meyer, Adam | Thayer Central High School | Nebraska | 772 |
| 34 | 22 | Chan, Christopher | John Bowne High School | Brooklyn-Queens-Staten Island | 772 |
| 35 | 45 | Wissmann, Ethan | Park Hill South High School | Kansas City | 760 |
| 36 | 44 | Conrad, Rebecca | Dover High School | Tuscawaras Valley Ohio | 753 |
| 37 | 30 | Henderson, Melanie | Riverdale High School | Oregon | 722 |
| 38 | 36 | Plunkert, Madison | Hereford High School | Western Maryland | 721 |
| 39 | 16 | Estrada, Ivan | Glencliff High School | Nashville | 641 |
| 40 | 42 | Peay, Kyle | Green River High School | Western Kentucky | 583 |
| Rank | Entry Num | Name | School | Region | Efficiency |
| 41 | 8 | Drilling, Joe | St. Thomas Aquinas High School | East Kansas | 548 |
| 42 | 10 | Hegermiller, Katherine | Sacred Heart Academy | Brookhaven National Laboratory | 539 |
| 43 | 15 | Okula, Trevor | Patchogue-Medford High School | Brookhaven National Laboratory | 529 |
| 44 | 6 | Ferracuti, Kristen | Lincoln Way East High School | Chicago South Suburban | 484 |
| 45 | 39 | Wolf, James | Marquette Catholic High School | Indiana | 481 |
| 46 | 24 | Pohland, Sara | Arundel High School | Maryland | 479 |
| 47 | 34 | Jamison, Leah | Westminster High School | Maryland | 392 |
| 48 | 5 | LaRosa, Chris | North Pocono High School | Northeast Pennsylvania | 382 |
| 49 | 33 | Corado, Valerie | Climax Springs R-IV High School | Jefferson City | 272 |
| 50 | 43 | Bennett, Sierra | Wellington High School | Palm Beach County | 244 |
| 51 | 9 | Carter, Jewelia | West Boca Raton High School | Palm Beach County | 207 |
| 52 | 1 | Roberts, Taylor | Climax Springs High School | Southwest Missouri | 121 |